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Unfolded protein response inhibitors cure group A streptococcal necrotizing fasciitis by modulating host asparagine.
Anand, Aparna; Sharma, Abhinay; Ravins, Miriam; Biswas, Debabrata; Ambalavanan, Poornima; Lim, Kimberly Xuan Zhen; Tan, Rachel Ying Min; Johri, Atul Kumar; Tirosh, Boaz; Hanski, Emanuel.
Afiliação
  • Anand A; Department of Microbiology and Molecular Genetics, The Institute for Medical Research, Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
  • Sharma A; Department of Microbiology and Molecular Genetics, The Institute for Medical Research, Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
  • Ravins M; Department of Microbiology and Molecular Genetics, The Institute for Medical Research, Israel-Canada (IMRIC), Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
  • Biswas D; Singapore-HUJ Alliance for Research and Enterprise, MMID Phase II, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore 117576, Singapore.
  • Ambalavanan P; Department of Microbiology and Immunology, National University of Singapore, Singapore 138602, Singapore.
  • Lim KXZ; Singapore-HUJ Alliance for Research and Enterprise, MMID Phase II, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore 117576, Singapore.
  • Tan RYM; Department of Microbiology and Immunology, National University of Singapore, Singapore 138602, Singapore.
  • Johri AK; Singapore-HUJ Alliance for Research and Enterprise, MMID Phase II, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore 117576, Singapore.
  • Tirosh B; Department of Microbiology and Immunology, National University of Singapore, Singapore 138602, Singapore.
  • Hanski E; Singapore-HUJ Alliance for Research and Enterprise, MMID Phase II, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore 117576, Singapore.
Sci Transl Med ; 13(605)2021 08 04.
Article em En | MEDLINE | ID: mdl-34349034
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Fasciite Necrosante Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Fasciite Necrosante Idioma: En Ano de publicação: 2021 Tipo de documento: Article