The effect of sumac (Rhus coriaria L.) supplementation on glycemic indices: A systematic review and meta-analysis of controlled clinical trials.
Complement Ther Med
; 61: 102766, 2021 Sep.
Article
em En
| MEDLINE
| ID: mdl-34365008
ABSTRACT
BACKGROUND & AIMS:
Rhus coriaria L. (Sumac) is a popular spice/herb with several biological functions owing to its antioxidant and insulin-like activities. Many clinical trials have indicated the potent anti-diabetic property of sumac but the results on few glycemic indices were inconclusive. Hence, this systematic review and meta-analysis were aimed to investigate sumac supplementation effect on glycemic indices.METHODS:
Systematically searched was performed by two independent reviewers using online databases including PubMed, Scopus, web of science, EMBASE from inception until November 2020. Data were pooled using a random-effects model and weighted mean difference (WMD) with 95 % confidence intervals (CI).RESULTS:
A total of 6 potentially relevant clinical trials met the inclusion criteria with total of 278 participants. Random-effects meta-analysis suggested no significant effects on the levels of fasting blood glucose [-7.08 mg/dl, 95 % CI -14.85 to 0.70,P = 0.07, I2 = 59.8 %], glycosylated hemoglobin (HbA1c) [-0.48 %, 95 % CI -1.01 to -0.04, P = 0.07, I2 = 0.0 %], homeostatic model assessment for insulin resistance (HOMA-IR) [-0.97, 95 % CI -1.96 to 0.02, P = 0.05, I2 = 83.8 %], and insulin [-2.94 Hedges' g, 95 % CI -6.67 to 0.80, P = 0.12, I2 = 83.1 %] following supplementation with sumac powder.CONCLUSION:
This meta-analysis showed no significant effects on any glycemic indices following supplementation with sumac powder.Palavras-chave
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MEDLINE
Assunto principal:
Rhus
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article