Emerging roles of alternative cleavage and polyadenylation (APA) in human disease.

Dharmalingam, Prakash; Mahalingam, Rajasekaran; Yalamanchili, Hari Krishna; Weng, Tingting; Karmouty-Quintana, Harry; Guha, Ashrith; A Thandavarayan, Rajarajan

Dharmalingam, Prakash; Mahalingam, Rajasekaran; Yalamanchili, Hari Krishna; Weng, Tingting; Karmouty-Quintana, Harry; Guha, Ashrith; A Thandavarayan, Rajarajan.

Afiliação

Dharmalingam P; Department of Biochemistry, Saveetha Dental College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, Chennai, India.
Mahalingam R; Laboratory of Neuroimmunology, Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Yalamanchili HK; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Weng T; Department of Pediatrics - Neurology, Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, Texas, USA.
Karmouty-Quintana H; Department of Pediatrics, USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA.
Guha A; Department of Biochemistry and Molecular Biology & Divisions of Critical Care, Pulmonary and Sleep Medicine, Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.
A Thandavarayan R; Department of Biochemistry and Molecular Biology & Divisions of Critical Care, Pulmonary and Sleep Medicine, Department of Internal Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.

J Cell Physiol ; 237(1): 149-160, 2022 01.

Article em En | MEDLINE | ID: mdl-34378793

Assuntos

Poliadenilação; Estabilidade de RNA; Regiões 3' não Traduzidas; Humanos; Estabilidade de RNA/genética; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Proteínas de Ligação a RNA/genética; Proteínas de Ligação a RNA/metabolismo

Palavras-chave

3'-UTR; RNA binding proteins; RNA biology; alternative cleavage and polyadenylation; mRNA maturation; polyadenylation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estabilidade de RNA / Poliadenilação Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estabilidade de RNA / Poliadenilação Idioma: En Ano de publicação: 2022 Tipo de documento: Article