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Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia.
Consonni, Michela; Garavaglia, Claudio; Grilli, Andrea; de Lalla, Claudia; Mancino, Alessandra; Mori, Lucia; De Libero, Gennaro; Montagna, Daniela; Casucci, Monica; Serafini, Marta; Bonini, Chiara; Häussinger, Daniel; Ciceri, Fabio; Bernardi, Massimo; Mastaglio, Sara; Bicciato, Silvio; Dellabona, Paolo; Casorati, Giulia.
Afiliação
  • Consonni M; Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, 20132, Italy.
  • Garavaglia C; Vita-Salute San Raffaele University, Milan, Italy.
  • Grilli A; Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, 20132, Italy.
  • de Lalla C; Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Mancino A; Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, 20132, Italy.
  • Mori L; Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, 20132, Italy.
  • De Libero G; Experimental Immunology, Department of Biomedicine, University of Basel and University Hospital, Basel, Switzerland.
  • Montagna D; Experimental Immunology, Department of Biomedicine, University of Basel and University Hospital, Basel, Switzerland.
  • Casucci M; Foundation IRCCS Policlinico San Matteo; Department of Sciences Clinic-Surgical, Diagnostic and Pediatric, University of Pavia, Pavia, Italy.
  • Serafini M; Innovative Immunotherapies Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Bonini C; M. Tettamanti Research Center, University of Milano-Bicocca, Monza, Italy.
  • Häussinger D; Experimental Hematology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Ciceri F; NMR-Laboratory, Department of Chemistry, University of Basel, Basel, Switzerland.
  • Bernardi M; Hematology and Bone Marrow Transplant Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Mastaglio S; Hematology and Bone Marrow Transplant Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Bicciato S; Hematology and Bone Marrow Transplant Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Dellabona P; Department of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Casorati G; Experimental Immunology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, 20132, Italy. dellabona.paolo@hsr.it.
Nat Commun ; 12(1): 4844, 2021 08 11.
Article em En | MEDLINE | ID: mdl-34381053
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doadores de Tecidos / Lisofosfolipídeos / Glicoproteínas / Receptores de Antígenos de Linfócitos T / Linfócitos T / Leucemia / Antígenos CD1 Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doadores de Tecidos / Lisofosfolipídeos / Glicoproteínas / Receptores de Antígenos de Linfócitos T / Linfócitos T / Leucemia / Antígenos CD1 Idioma: En Ano de publicação: 2021 Tipo de documento: Article