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Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration.
Carrasco, Manuel J; Alishetty, Suman; Alameh, Mohamad-Gabriel; Said, Hooda; Wright, Lacey; Paige, Mikell; Soliman, Ousamah; Weissman, Drew; Cleveland, Thomas E; Grishaev, Alexander; Buschmann, Michael D.
Afiliação
  • Carrasco MJ; Department of Bioengineering, George Mason University, Fairfax, VA, USA.
  • Alishetty S; Department of Bioengineering, George Mason University, Fairfax, VA, USA.
  • Alameh MG; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Said H; Department of Bioengineering, George Mason University, Fairfax, VA, USA.
  • Wright L; Department of Bioengineering, George Mason University, Fairfax, VA, USA.
  • Paige M; Department of Chemistry & Biochemistry, George Mason University, Fairfax, VA, USA.
  • Soliman O; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Weissman D; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Cleveland TE; Institute for Bioscience and Biotechnology Research National Institute of Standards and Technology, Rockville, MD, USA.
  • Grishaev A; Institute for Bioscience and Biotechnology Research National Institute of Standards and Technology, Rockville, MD, USA.
  • Buschmann MD; Department of Bioengineering, George Mason University, Fairfax, VA, USA. mbuschma@gmu.edu.
Commun Biol ; 4(1): 956, 2021 08 11.
Article em En | MEDLINE | ID: mdl-34381159
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Expressão Gênica / Nanopartículas / Íons / Lipídeos Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Expressão Gênica / Nanopartículas / Íons / Lipídeos Idioma: En Ano de publicação: 2021 Tipo de documento: Article