SK1 Inhibitor RB005 Induces Apoptosis in Colorectal Cancer Cells through SK1 Inhibition Dependent and Independent Pathway.

Shrestha, Jitendra; Shamshiddinova, Maftuna; Lee, Yong-Moon; Oh, Yoon Sin; Baek, Dong Jae; Park, Eun-Young

Shrestha, Jitendra; Shamshiddinova, Maftuna; Lee, Yong-Moon; Oh, Yoon Sin; Baek, Dong Jae; Park, Eun-Young.

Afiliação

Shrestha J; College of Pharmacy, Mokpo National University, Jeonnam, Korea.
Shamshiddinova M; College of Pharmacy, Chungbuk National University, Cheongju, Korea.
Lee YM; College of Pharmacy, Chungbuk National University, Cheongju, Korea.
Oh YS; Department of Food and Nutrition, Eulji University, Seongnam, Korea.
Baek DJ; College of Pharmacy, Mokpo National University, Jeonnam, Korea.
Park EY; College of Pharmacy, Mokpo National University, Jeonnam, Korea.

Curr Mol Pharmacol ; 15(3): 570-581, 2022.

Article em En | MEDLINE | ID: mdl-34382511

Assuntos

Neoplasias do Colo; Neoplasias Colorretais; Apoptose; Ceramidas/metabolismo; Ceramidas/farmacologia; Neoplasias Colorretais/tratamento farmacológico; Cloridrato de Fingolimode/farmacologia; Humanos; RNA Interferente Pequeno/genética

Palavras-chave

CRC; PF543; RB005; SK1 inhibitor; Sphingosine kinase inhibitor; apoptosis; colorectal cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias do Colo Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias do Colo Idioma: En Ano de publicação: 2022 Tipo de documento: Article