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Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior.
Blaze, J; Navickas, A; Phillips, H L; Heissel, S; Plaza-Jennings, A; Miglani, S; Asgharian, H; Foo, M; Katanski, C D; Watkins, C P; Pennington, Z T; Javidfar, B; Espeso-Gil, S; Rostandy, B; Alwaseem, H; Hahn, C G; Molina, H; Cai, D J; Pan, T; Yao, W D; Goodarzi, H; Haghighi, F; Akbarian, S.
Afiliação
  • Blaze J; Department of Neuroscience, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Navickas A; Friedman Brain Institute, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Phillips HL; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.
  • Heissel S; Departments of Psychiatry and Behavioral Sciences, Neuroscience and Physiology, Upstate Medical University, Syracuse, NY, USA.
  • Plaza-Jennings A; The Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY, USA.
  • Miglani S; Department of Psychiatry, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Asgharian H; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.
  • Foo M; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.
  • Katanski CD; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.
  • Watkins CP; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.
  • Pennington ZT; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.
  • Javidfar B; Department of Neuroscience, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Espeso-Gil S; Friedman Brain Institute, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Rostandy B; Friedman Brain Institute, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Alwaseem H; Department of Psychiatry, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Hahn CG; Friedman Brain Institute, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Molina H; Department of Psychiatry, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Cai DJ; The Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY, USA.
  • Pan T; The Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY, USA.
  • Yao WD; Department of Neurosciences, Thomas Jefferson University, Philadelphia, PA, USA.
  • Goodarzi H; The Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY, USA.
  • Haghighi F; Department of Neuroscience, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
  • Akbarian S; Friedman Brain Institute, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
Nat Commun ; 12(1): 4913, 2021 08 13.
Article em En | MEDLINE | ID: mdl-34389722
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA de Transferência / Transmissão Sináptica / Proteoma / Epigênese Genética / Transtorno Depressivo / Metiltransferases Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA de Transferência / Transmissão Sináptica / Proteoma / Epigênese Genética / Transtorno Depressivo / Metiltransferases Idioma: En Ano de publicação: 2021 Tipo de documento: Article