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Developing an IV Ketamine Clinic for Treatment-Resistant Depression: a Primer.
Parikh, Sagar V; Lopez, Daniela; Vande Voort, Jennifer L; Rico, Jose; Achtyes, Eric; Coryell, William; Goddard, Andrew; Goes, Fernando; Greden, John F; Singh, Balwinder; Kaplin, Adam; Frye, Mark A; Maixner, Daniel; Watson, Brendon; Drake, Karina; Tarnal, Vijay; Riva-Posse, Patricio; Bobo, William V.
Afiliação
  • Parikh SV; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Lopez D; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Vande Voort JL; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Rico J; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Achtyes E; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Coryell W; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Goddard A; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Goes F; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Greden JF; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Singh B; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Kaplin A; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Frye MA; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Maixner D; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Watson B; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Drake K; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Tarnal V; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Riva-Posse P; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Bobo WV; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
  • Bio-K Study Team; Parikh, MD, Lopez, MS, Maixner, MD, Watson, MD, Drake, MD, Bio-K Study Team, Department of Psychiatry and Depression Center, University of Michigan, Ann Arbor, Michigan. Voort, MD, Rico, MBA, Singh, MD, Frye, MD, Bobo, MD, Bio-K Study Team, Department of Psychiatry and Psychology, Mayo Clinic, Roche
Psychopharmacol Bull ; 51(3): 109-124, 2021 06 01.
Article em En | MEDLINE | ID: mdl-34421148
ABSTRACT
The efficacy of subanesthetic intravenous ketamine for treatment resistant depression (TRD) has spurred a growth of clinics nationwide that provide this service. Ketamine is an FDA-approved drug as an anesthetic but remains unapproved for psychiatric indications, and this status raises a number of short- and long-term safety and efficacy concerns that need to be addressed when implementing and developing this type of clinic. Using a framework of systems, provider, and patient domains, we provide a review of the key challenges in providing ketamine infusions and suggest potential approaches. Under systems issues, we highlight broad stakeholder engagement involving cross-departmental and multidisciplinary considerations, business case development, and delineation of administrative standard operating procedures. In the provider domain, we highlight specific roles for different treatment team members as well as suggested training requirements. In the patient domain, we identify a variety of standard operating procedures involving initial patient assessment parameters, ketamine dosing and administration guidelines, and safety monitoring procedures. Together, this review provides key considerations for developing a ketamine clinic for depression, in an effort to meet the pressing demand for this novel treatment option while helping to ensure its safe implementation.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Resistente a Tratamento / Ketamina Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Resistente a Tratamento / Ketamina Idioma: En Ano de publicação: 2021 Tipo de documento: Article