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Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals.
Parker, Joanne L; Deme, Justin C; Wu, Zhiyi; Kuteyi, Gabriel; Huo, Jiandong; Owens, Raymond J; Biggin, Philip C; Lea, Susan M; Newstead, Simon.
Afiliação
  • Parker JL; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK. simon.newstead@bioch.ox.ac.uk joanne.parker@bioch.ox.ac.uk susan.lea@path.ox.ac.uk philip.biggin@bioch.ox.ac.uk.
  • Deme JC; Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
  • Wu Z; Central Oxford Structural Molecular Imaging Centre, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.
  • Kuteyi G; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
  • Huo J; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
  • Owens RJ; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
  • Biggin PC; Structural Biology, The Rosalind Franklin Institute, Harwell Science and Innovation Campus, Didcot, UK.
  • Lea SM; Division of Structural Biology, The Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Newstead S; Protein Production UK, The Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, UK.
Sci Adv ; 7(35)2021 08.
Article em En | MEDLINE | ID: mdl-34433568
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Simportadores Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Simportadores Idioma: En Ano de publicação: 2021 Tipo de documento: Article