The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia.

Niederkorn, Madeline; Ishikawa, Chiharu; M Hueneman, Kathleen; Bartram, James; Stepanchick, Emily; R Bennett, Joshua; E Culver-Cochran, Ashley; Bolanos, Lyndsey C; Uible, Emma; Choi, Kwangmin; Wunderlich, Mark; Perentesis, John P; M Chlon, Timothy; Filippi, Marie-Dominique; Starczynowski, Daniel T

Niederkorn, Madeline; Ishikawa, Chiharu; M Hueneman, Kathleen; Bartram, James; Stepanchick, Emily; R Bennett, Joshua; E Culver-Cochran, Ashley; Bolanos, Lyndsey C; Uible, Emma; Choi, Kwangmin; Wunderlich, Mark; Perentesis, John P; M Chlon, Timothy; Filippi, Marie-Dominique; Starczynowski, Daniel T.

Afiliação

Niederkorn M; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Ishikawa C; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
M Hueneman K; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Bartram J; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Stepanchick E; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
R Bennett J; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
E Culver-Cochran A; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Bolanos LC; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Uible E; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Choi K; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Wunderlich M; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Perentesis JP; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
M Chlon T; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Filippi MD; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Starczynowski DT; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Leukemia ; 36(2): 438-451, 2022 02.

Article em En | MEDLINE | ID: mdl-34465865

Assuntos

Proteína 1 Associada a ECH Semelhante a Kelch/metabolismo; Leucemia Mieloide Aguda/patologia; Fator 2 Relacionado a NF-E2/metabolismo; Estresse Oxidativo; Proteases Específicas de Ubiquitina/metabolismo; Proteases Específicas de Ubiquitina/fisiologia; Animais; Apoptose; Proliferação de Células; Feminino; Humanos; Proteína 1 Associada a ECH Semelhante a Kelch/genética; Leucemia Mieloide Aguda/genética; Leucemia Mieloide Aguda/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Fator 2 Relacionado a NF-E2/genética; Oxirredução; Prognóstico; Transdução de Sinais; Células Tumorais Cultivadas; Proteases Específicas de Ubiquitina/genética; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Estresse Oxidativo / Fator 2 Relacionado a NF-E2 / Proteases Específicas de Ubiquitina / Proteína 1 Associada a ECH Semelhante a Kelch Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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