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Increase in lamin B1 promotes telomere instability by disrupting the shelterin complex in human cells.
Pennarun, Gaëlle; Picotto, Julien; Etourneaud, Laure; Redavid, Anna-Rita; Certain, Anaïs; Gauthier, Laurent R; Fontanilla-Ramirez, Paula; Busso, Didier; Chabance-Okumura, Caroline; Thézé, Benoît; Boussin, François D; Bertrand, Pascale.
Afiliação
  • Pennarun G; Université de Paris and Université Paris-Saclay, INSERM, iRCM/IBFJ CEA, UMR Stabilité Génétique Cellules Souches et Radiations, F-92265 Fontenay-aux-Roses, France.
  • Picotto J; "DNA Repair and Ageing" Team, iRCM/IBFJ, DRF, CEA, Fontenay-aux-Roses, France.
  • Etourneaud L; Université de Paris and Université Paris-Saclay, INSERM, iRCM/IBFJ CEA, UMR Stabilité Génétique Cellules Souches et Radiations, F-92265 Fontenay-aux-Roses, France.
  • Redavid AR; "DNA Repair and Ageing" Team, iRCM/IBFJ, DRF, CEA, Fontenay-aux-Roses, France.
  • Certain A; Université de Paris and Université Paris-Saclay, INSERM, iRCM/IBFJ CEA, UMR Stabilité Génétique Cellules Souches et Radiations, F-92265 Fontenay-aux-Roses, France.
  • Gauthier LR; "DNA Repair and Ageing" Team, iRCM/IBFJ, DRF, CEA, Fontenay-aux-Roses, France.
  • Fontanilla-Ramirez P; Université de Paris and Université Paris-Saclay, INSERM, iRCM/IBFJ CEA, UMR Stabilité Génétique Cellules Souches et Radiations, F-92265 Fontenay-aux-Roses, France.
  • Busso D; "DNA Repair and Ageing" Team, iRCM/IBFJ, DRF, CEA, Fontenay-aux-Roses, France.
  • Chabance-Okumura C; Université de Paris and Université Paris-Saclay, INSERM, iRCM/IBFJ CEA, UMR Stabilité Génétique Cellules Souches et Radiations, F-92265 Fontenay-aux-Roses, France.
  • Thézé B; "DNA Repair and Ageing" Team, iRCM/IBFJ, DRF, CEA, Fontenay-aux-Roses, France.
  • Boussin FD; Université de Paris and Université Paris-Saclay, INSERM, iRCM/IBFJ CEA, UMR Stabilité Génétique Cellules Souches et Radiations, F-92265 Fontenay-aux-Roses, France.
  • Bertrand P; "Radiopathology" Team, iRCM/IBFJ, DRF, CEA, Fontenay-aux-Roses, France.
Nucleic Acids Res ; 49(17): 9886-9905, 2021 09 27.
Article em En | MEDLINE | ID: mdl-34469544
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Telômero / Proteína 2 de Ligação a Repetições Teloméricas / Lamina Tipo B / Complexo Shelterina Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Telômero / Proteína 2 de Ligação a Repetições Teloméricas / Lamina Tipo B / Complexo Shelterina Idioma: En Ano de publicação: 2021 Tipo de documento: Article