Cannabidiol and the corticoraphe circuit in post-traumatic stress disorder.
IBRO Neurosci Rep
; 11: 88-102, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-34485973
2-AG, 2-arachidonoylglycerol; 5-HT, Serotonin; 5-HT1AR, 5-HT Receptor Type 1A; 5-HT2AR, 5-HT Receptor Type 2 A; AEA, Anandamide; CB1R, Cannabinoid Receptor Type 1; CB2R, Cannabinoid Receptor Type 2; CBD, Cannabidiol; COVID-19, SARS-CoV-2; Cannabidiol; DRN, Dorsal Raphe Nucleus; ERK1/2, Extracellular Signal-Related Kinases Type 1 or Type 2; FAAH, Fatty Acid Amide Hydrolase; GABA, Gamma-Aminobutyric Acid; GPCRs, G-Protein Coupled Receptors; NMDAR, N-Methyl-D-aspartate Receptors; PET, Positron Emission Tomography; PFC, DRN and Raphe; PFC, Prefrontal Cortex; PTSD; PTSD, Post-Traumatic Stress Disorder; SSNRI, Selective Norepinephrine Reuptake Inhibitor; SSRI, Selective Serotonin Reuptake Inhibitor; Serotonin; TRPV1, Transient Receptor Potential Vanilloid 1 Channels; Traumatic Stress; fMRI, Functional Magnetic Resonance Imaging; mPFC, Medial Prefrontal Cortex
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2021
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Article