Silencing of PFKFB3 protects podocytes against high glucose­induced injury by inducing autophagy.

Zhu, Zhengming; Liu, Qingsheng; Sun, Jianshi; Bao, Ziyang; Wang, Weiwei

Silencing of PFKFB3 protects podocytes against high glucoseinduced injury by inducing autophagy.

Zhu, Zhengming; Liu, Qingsheng; Sun, Jianshi; Bao, Ziyang; Wang, Weiwei.

Afiliação

Zhu Z; Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang 310007, P.R. China.
Liu Q; Department of Geriatrics, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang 310007, P.R. China.
Sun J; Department of Nephrology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, P.R. China.
Bao Z; Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang 310007, P.R. China.
Wang W; Department of Nephrology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang 310007, P.R. China.

Mol Med Rep ; 24(5)2021 Nov.

Article em En | MEDLINE | ID: mdl-34490476

Assuntos

Autofagia/efeitos dos fármacos; Nefropatias Diabéticas/metabolismo; Glucose/metabolismo; Fosfofrutoquinase-2/fisiologia; Podócitos/metabolismo; Animais; Linhagem Celular; Humanos; Camundongos; Podócitos/patologia

Palavras-chave

6-biphosphatase 3; 6phosphofructo2-kinase/fructose-2; autophagy; diabetic nephropathy; high glucose; podocyte

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Fosfofrutoquinase-2 / Nefropatias Diabéticas / Podócitos / Glucose Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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