[Feasibility of Preheating at 41 â to Correct Red Blood Cell Parameters in the Presence of High-titer Cold Agglutinins].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
; 43(4): 507-512, 2021 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-34494519
ABSTRACT
Objective To explore the feasibility of preheating in 41 â water bath for 30 minutes to correct the red blood cell parameters in the specimens containing high-titer cold agglutinins(CAs). Methods Two specimens containing high-titer CAs were selected during work,and the parameters of complete blood count at room temperature or after preheating in 37 â or 41 â water bath were compared.The smears were stained,and the distribution of red blood cells was observed with a microscope.Further,74 specimens without CAs were collected for complete blood count,and then the test results at room temperature and after preheating at 41 â were compared. Results At room temperature,the specimens containing high-titer CAs showed significantly reduced red blood cell count(RBC)and hematocrit(HCT),abnormally increased mean corpuscular hemoglobin(MCH)and mean cell hemoglobin concentration(MCHC),abnormal percents of hemoglobin(HGB)and RBC,and aggregation of a large number of red blood cells.After being preheated at 37 â for a certain time,the specimens demonstrated obviously improved parameters while still aggregation of a small number of red blood cells.After being preheated at 41 â for 30 minutes,the specimens showed significantly increased RBC,normal HCT,MCH,and MCHC,and evenly distributed red blood cells.The 74 specimens without CAs showed the comparability was ≥80% between room temperature and preheating at 41 â for 30 minutes or 60 minutes. Conclusion We can preheat the specimens containing high-titer CAs in a water bath at 41 â to obtain accurate red blood cell parameters.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Eritrócitos
Idioma:
Zh
Ano de publicação:
2021
Tipo de documento:
Article