Linear-Dendritic Polymer-Platinum Complexes Forming Well-Defined Nanocapsules for Acid-Responsive Drug Delivery.

Liu, Kexin; Xiang, Jiajia; Wang, Guowei; Xu, Hongxia; Piao, Ying; Liu, Xiangrui; Tang, Jianbin; Shen, Youqing; Zhou, Zhuxian

Liu, Kexin; Xiang, Jiajia; Wang, Guowei; Xu, Hongxia; Piao, Ying; Liu, Xiangrui; Tang, Jianbin; Shen, Youqing; Zhou, Zhuxian.

Afiliação

Liu K; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Xiang J; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Wang G; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Xu H; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Piao Y; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Liu X; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Tang J; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Shen Y; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Zhou Z; Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 311215, China.

ACS Appl Mater Interfaces ; 13(37): 44028-44040, 2021 Sep 22.

Article em En | MEDLINE | ID: mdl-34499483

Assuntos

Antineoplásicos/uso terapêutico; Cisplatino/uso terapêutico; Portadores de Fármacos/química; Nanocápsulas/química; Neoplasias/tratamento farmacológico; Animais; Antineoplásicos/química; Antineoplásicos/farmacocinética; Apoptose/efeitos dos fármacos; Linhagem Celular Tumoral; Cisplatino/química; Cisplatino/farmacocinética; Complexos de Coordenação/química; Complexos de Coordenação/farmacocinética; Dendrímeros/química; Dendrímeros/farmacocinética; Portadores de Fármacos/farmacocinética; Liberação Controlada de Fármacos; Humanos; Camundongos Endogâmicos BALB C; Platina/química; Platina/farmacocinética; Polietilenoglicóis/química; Polietilenoglicóis/farmacocinética; Polilisina/química; Polilisina/farmacocinética; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

controlled release; platinum drug delivery; polymeric nanocapsule; self-assembly; well-defined structure

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Cisplatino / Nanocápsulas / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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