Your browser doesn't support javascript.
loading
A sequentially activated bioluminescent probe for observation of cellular H2O2 production induced by cysteine.
Ma, Kaiqing; Yue, Yongkang; Zhao, Lingling; Chao, Jianbin; Yin, Caixia.
Afiliação
  • Ma K; Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. yincx@sxu.edu.cn.
  • Yue Y; Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. yincx@sxu.edu.cn.
  • Zhao L; Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. yincx@sxu.edu.cn.
  • Chao J; Research Institute of Applied Chemistry, Shanxi University, Taiyuan 030006, China.
  • Yin C; Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. yincx@sxu.edu.cn.
Chem Commun (Camb) ; 57(78): 10015-10018, 2021 Sep 30.
Article em En | MEDLINE | ID: mdl-34505120
ABSTRACT
We report herein a caged luciferin probe Cy-Hy as a sequentially activated probe to selectively and sensitively sense L-Cys and H2O2. The probe displayed fluorescence and bioluminescence responses toward the two analytes. Utilizing the present probe, cellular excess L-Cys-induced H2O2 up-regulation was observed for the first time in living MDA-MB-231 cells.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína / Corantes Fluorescentes / Peróxido de Hidrogênio Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína / Corantes Fluorescentes / Peróxido de Hidrogênio Idioma: En Ano de publicação: 2021 Tipo de documento: Article