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A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation.
Charles, Rebecca L; Abis, Giancarlo; Fernandez, Beatriz F; Guttzeit, Sebastian; Buccafusca, Roberto; Conte, Maria R; Eaton, Philip.
Afiliação
  • Charles RL; Queen Mary University of London, William Harvey Research Institute, Charterhouse Square, London, EC1M 6BQ, UK.
  • Abis G; King's College London, Randall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, London, SE1 1UL, UK.
  • Fernandez BF; King's College London, The British Heart Foundation Centre of Excellence, The Rayne Institute, St Thomas' Hospital, London, SE1 7EH, UK.
  • Guttzeit S; King's College London, The British Heart Foundation Centre of Excellence, The Rayne Institute, St Thomas' Hospital, London, SE1 7EH, UK.
  • Buccafusca R; Queen Mary University of London, School of Biological and Chemical Sciences, Mile End Road, London, E1 4NS, UK.
  • Conte MR; King's College London, Randall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, London, SE1 1UL, UK. Electronic address: sasi.conte@kcl.ac.uk.
  • Eaton P; Queen Mary University of London, William Harvey Research Institute, Charterhouse Square, London, EC1M 6BQ, UK. Electronic address: p.eaton@qmul.ac.uk.
Redox Biol ; 46: 102107, 2021 10.
Article em En | MEDLINE | ID: mdl-34509915
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Sulfidrila / Epóxido Hidrolases Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Sulfidrila / Epóxido Hidrolases Idioma: En Ano de publicação: 2021 Tipo de documento: Article