Improved anti-cancer effect of epidermal growth factor-gold nanoparticle conjugates by protein orientation through site-specific mutagenesis.

Zhang, Aiwen; Nakanishi, Jun.

Afiliação

Zhang A; Graduate School of Advanced Science and Engineering, Waseda University, Shinjuku-ku, Tokyo, Japan.
Nakanishi J; Research Center for Functional Materials, National Institute for Materials Science (NIMS), Tsukuba, Japan.

Sci Technol Adv Mater ; 22(1): 616-626, 2021.

Article em En | MEDLINE | ID: mdl-34512175

Palavras-chave

211 Scaffold / Tissue engineering/Drug delivery; 212 Surface and interfaces, Nanoparticles; 30 Bio-inspired and biomedical materials; EGF-nanoparticle conjugates; Nanomedicine; binding activity; growth inhibition; phosphorylation signaling; protein orientation

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article