Schrödinger's T Cells: Molecular Insights Into Stemness and Exhaustion.

Gonzalez, Nancy M; Zou, Dawei; Gu, Andy; Chen, Wenhao

Gonzalez, Nancy M; Zou, Dawei; Gu, Andy; Chen, Wenhao.

Afiliação

Gonzalez NM; Immunobiology & Transplant Science Center, Department of Surgery, Houston Methodist Research Institute & Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, United States.
Zou D; College of Medicine, Texas A&M Health Science Center, College Station, TX, United States.
Gu A; Immunobiology & Transplant Science Center, Department of Surgery, Houston Methodist Research Institute & Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, United States.
Chen W; Immunobiology & Transplant Science Center, Department of Surgery, Houston Methodist Research Institute & Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX, United States.

Front Immunol ; 12: 725618, 2021.

Article em En | MEDLINE | ID: mdl-34512656

Assuntos

Imunoterapia/métodos; Neoplasias/imunologia; Infecção Persistente/imunologia; Linfócitos T/fisiologia; Diferenciação Celular; Epigênese Genética; Neoplasias/terapia; Infecção Persistente/terapia

Palavras-chave

T cell; T cell exhaustion; T cell stemness; epigenetic regulation; transcription factor; transplantation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Infecção Persistente / Imunoterapia / Neoplasias Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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