Cataract extraction and intraocular pressure-lowering agents delivery: A nationwide French study between 2005 and 2017.
Eur J Ophthalmol
; 32(4): 2201-2210, 2022 Jul.
Article
em En
| MEDLINE
| ID: mdl-34569353
ABSTRACT
PURPOSE:
Cataract and glaucoma are among the leading causes of blindness worldwide in older people, and they are often concomitant. To assess topical intraocular (IOP)-lowering agents delivery changes after cataract extraction. MATERIAL ANDMETHODS:
Longitudinal matched exposed-unexposed study from the French national healthcare database from January 1, 2005 to January 1, 2017. We compared individuals using topical IOP-lowering agents who underwent bilateral cataract extraction with individuals matched on IOP-lowering agents load, age, and sex who did not undergo cataract extraction. IOP-lowering agents number of drops was assessed 12 months before the first cataract extraction and compared with number of drops 12 months after the second cataract extraction.RESULTS:
About 1194 individuals treated with IOP-lowering agents were included, 597 exposed to bilateral cataract extraction and 597 unexposed to any surgery (total mean age 74.8 ± 8.3 years; 69.0% women). Mean IOP-lowering agents delivery at baseline was 1.4 daily drops in both groups. The mean number of drops decreased greater in the exposed than unexposed group (-25.5% vs -3.5%; p < 0.0001). Overall, 159 (26.6%) and 48 (8.0%) individuals in the exposed and unexposed groups interrupted medication (p < 0.0001).CONCLUSIONS:
A decrease of around one quarter of IOP-lowering agents delivery was observed after cataract extraction in the present real-life study with a longstanding interruption observed in one quarter of patients. Phacoemulsification as a standalone procedure reduces IOP-lowering agents delivery in ocular hypertension and glaucoma.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Catarata
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Extração de Catarata
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Glaucoma
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Hipertensão Ocular
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Facoemulsificação
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article