Outcome After Acute Ischemic Stroke Treatment During Covid-19 Outbreak in South-East Tuscany.
Cardiovasc Hematol Disord Drug Targets
; 21(3): 179-184, 2021.
Article
em En
| MEDLINE
| ID: mdl-34579640
ABSTRACT
BACKGROUND:
During Covid-19 pandemic, the Italian National Healthcare Service has faced increasing pressure, especially in Northern Italy. Even in less-affected regions, such as Tuscany, the changes in the healthcare system to prevent Covid-19 spread resulted in difficulty in treating time-dependent disorders like ischemic stroke rapidly.OBJECTIVE:
The aim of our study was to assess the outcome after acute ischemic stroke treatments during the Covid-19 spread in comparison with a similar period of the previous year in Siena-Hospital (Hub center in the South-East Tuscany).METHODS:
We enrolled all patients admitted to Siena-Hospital for ischemic stroke and submitted them to acute treatments (intravenous and/or mechanical thrombolysis) between February 21st and May 18th, 2020 (study group, n38) and compared the results with ischemic strokes acutely treated in a similar period in 2019 (control group, n39). The modified Rankin scale score was assessed at 90 days to evaluate a 3-month clinical outcome.RESULTS:
In the study group, the time from symptoms onset to hospital arrival and the door-to-groin puncture time were significantly more prolonged than in the control group. In moderate-severe strokes, the 3-month mortality was significantly higher in the study group (31% vs. 6%; p=0.01), and the number of patients with poor functional outcomes was significantly higher in the study group (73% vs. 44%; p=0.03).CONCLUSION:
During the lockdown period due to Covid-19 pandemic, patients with acute ischemic stroke had a worse prognosis. These findings suggest the need to improve the health system organization to guarantee an appropriate treatment during the pandemic, including the patients that are not affected by Covid-19.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Isquemia Encefálica
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Acidente Vascular Cerebral
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AVC Isquêmico
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COVID-19
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article