RNA N<sup>6</sup> -methyladenosine modification in the lethal teamwork of cancer stem cells and the tumor immune microenvironment: Current landscape and therapeutic potential.

Zhang, Zhihui; Zhang, Chaoqi; Luo, Yuejun; Zhang, Guochao; Wu, Peng; Sun, Nan; He, Jie

RNA N⁶ -methyladenosine modification in the lethal teamwork of cancer stem cells and the tumor immune microenvironment: Current landscape and therapeutic potential.

Zhang, Zhihui; Zhang, Chaoqi; Luo, Yuejun; Zhang, Guochao; Wu, Peng; Sun, Nan; He, Jie.

Afiliação

Zhang Z; Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhang C; Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Luo Y; Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhang G; Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wu P; Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Sun N; Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
He J; Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Clin Transl Med ; 11(9): e525, 2021 09.

Article em En | MEDLINE | ID: mdl-34586737

Assuntos

Adenosina/análogos & derivados; Células-Tronco Neoplásicas; Processamento Pós-Transcricional do RNA; Microambiente Tumoral; Adenosina/genética; Adenosina/imunologia; Adenosina/metabolismo; Animais; Antineoplásicos; Resistencia a Medicamentos Antineoplásicos/genética; Resistencia a Medicamentos Antineoplásicos/imunologia; Humanos; Inibidores de Checkpoint Imunológico; Imunoterapia; Camundongos; Neoplasias/genética; Neoplasias/metabolismo; Neoplasias/patologia; Células-Tronco Neoplásicas/imunologia; Células-Tronco Neoplásicas/metabolismo; Células-Tronco Neoplásicas/patologia; Processamento Pós-Transcricional do RNA/genética; Processamento Pós-Transcricional do RNA/imunologia; Microambiente Tumoral/genética; Microambiente Tumoral/imunologia

Palavras-chave

PD-1; PD-L1; cancer stem cells; immune checkpoint; immunotherapy; m6A modification; metastasis; recurrence; therapeutic resistance; tumor immune microenvironment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Adenosina / Processamento Pós-Transcricional do RNA / Microambiente Tumoral Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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