Thermally induced silane dehydrocoupling on porous silicon nanoparticles for ultra-long-acting drug release.
Nanoscale
; 13(37): 15560-15568, 2021 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-34596178
ABSTRACT
Here, we report an ultra-long-acting drug release nano-formulation based on porous silicon nanoparticles (pSiNPs) that are prepared by thermally induced silane dehydrocoupling and lipid-coating. This robust formulation offers the ability to release an anticancer drug, for up to 2 weeks, in various biological environments; pH 7.4 buffer, cancer cells, and tumor xenograft model.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Silício
/
Nanopartículas
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article