Computed tomography-guided partial-breast brachytherapy using implanted catheters as fiducial markers versus co-registered magnetic resonance imaging.
Brachytherapy
; 20(6): 1219-1225, 2021.
Article
em En
| MEDLINE
| ID: mdl-34602344
ABSTRACT
PURPOSE:
Partial-breast irradiation (PBI) needs accurate cavity delineation with computed tomography (CT). In perioperative PBI using multicatheter-interstitial brachytherapy (MIB), catheters implanted during surgery were enabled as fiducial markers. Magnetic resonance imaging (MRI) can also assist delineation with CT.METHODS:
Patients receiving MIB-PBI were analyzed. Cavity visualization scores (CVSs) were categorized with CT. With catheter-based delineation (CBD), the relationship between cavity boundaries and catheters were used to contour the tumor bed. Co-registered MRI delineation (CMD) was also performed. The correlation between cavity volume and the excised tissue weight was compared for the two techniques.RESULTS:
The association between CVS and preoperative characteristics in 159 patients showed mammographic breast density (MBD) remained correlated to CVS on multiple regression analyses; CVSâ¯=â¯5.2-0.61 x MBD (p < 0.0001). In 43 patients, the cavity volumes determined with CBD vs CMD were 12.8⯱â¯6.4 cm3 vs 16.1⯱â¯12.4 cm3 (p < 0.0001), and their plots with excised weights showed the best fitting lines were 0.29â¯vs 0.48 (p < 0.0001), respectively. The correlation coefficients for CBD vs CMD were 0.65â¯vs 0.55 (pâ¯=â¯0.20) in low (CVS 1-3, nâ¯=â¯27) and 0.72â¯vs 0.58 (pâ¯=â¯0.36) in high visualized cavities (CVS 4-5, nâ¯=â¯16), respectively.CONCLUSIONS:
The use of implanted catheters as fiducial markers was associated with smaller cavities and greater correlations with the excised tissue weights than co-registration with MRI. This might be a useful technique, especially for patients with dense breasts on mammography.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Braquiterapia
/
Neoplasias da Mama
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article