Terpene-rich fractions of Ficus mucoso (Welw) modulate lipopolysaccharide-induced inflammatory mediators and aberrant permeability of the inner mitochondrial membrane in murine animal model.

Oyebode, Olubukola Titilope; Olanlokun, John Oludele; Salami, Olamilekan; Obi, Ifeanyi; Bodede, Olusola; Prinsloo, Gerhard; Olorunsogo, Olufunso Olabode

Oyebode, Olubukola Titilope; Olanlokun, John Oludele; Salami, Olamilekan; Obi, Ifeanyi; Bodede, Olusola; Prinsloo, Gerhard; Olorunsogo, Olufunso Olabode.

Afiliação

Oyebode OT; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. bukioyebode@gmail.com.
Olanlokun JO; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Salami O; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Obi I; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Bodede O; Department of Agriculture and Animal Health, Florida Campus, University of South Africa, Florida, 1710, South Africa.
Prinsloo G; Department of Agriculture and Animal Health, Florida Campus, University of South Africa, Florida, 1710, South Africa.
Olorunsogo OO; Laboratories for Biomembrane Research and Biotechnology, Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.

Inflammopharmacology ; 29(6): 1733-1749, 2021 Dec.

Article em En | MEDLINE | ID: mdl-34613566

Assuntos

Anti-Inflamatórios/farmacologia; Ficus/química; Extratos Vegetais/farmacologia; Terpenos/farmacologia; Animais; Anti-Inflamatórios/isolamento & purificação; Cromatografia Líquida de Alta Pressão; Citocinas/metabolismo; Modelos Animais de Doenças; Inflamação/tratamento farmacológico; Mediadores da Inflamação/metabolismo; Lipopolissacarídeos; Fígado/efeitos dos fármacos; Fígado/patologia; Masculino; Espectrometria de Massas; Camundongos; Membranas Mitocondriais/efeitos dos fármacos; Membranas Mitocondriais/metabolismo; Permeabilidade; Terpenos/isolamento & purificação

Palavras-chave

Inflammation; Lipopolysaccharide; Mitochondrial swelling; Pro-inflammatory cytokines

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terpenos / Extratos Vegetais / Ficus / Anti-Inflamatórios Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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