Immunogenic T cell epitopes of SARS-CoV-2 are recognized by circulating memory and naïve CD8 T cells of unexposed individuals.

Quiros-Fernandez, Isaac; Poorebrahim, Mansour; Fakhr, Elham; Cid-Arregui, Angel

Quiros-Fernandez, Isaac; Poorebrahim, Mansour; Fakhr, Elham; Cid-Arregui, Angel.

Afiliação

Quiros-Fernandez I; Targeted Tumor Vaccines Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Poorebrahim M; Targeted Tumor Vaccines Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Fakhr E; Targeted Tumor Vaccines Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Cid-Arregui A; Targeted Tumor Vaccines Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address: a.cid@dkfz-heidelberg.de.

EBioMedicine ; 72: 103610, 2021 Oct.

Article em En | MEDLINE | ID: mdl-34627082

Assuntos

Linfócitos T CD8-Positivos/imunologia; COVID-19/imunologia; Epitopos de Linfócito T/imunologia; SARS-CoV-2/imunologia; Simulação por Computador; Reações Cruzadas; Humanos; Imunoterapia; Receptores de Antígenos de Linfócitos T

Palavras-chave

CD8 memory T cells; COVID-19; SARS-CoV-2; T cell epitopes; immunotherapy; pre-existing cross-reactivity; vaccine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Epitopos de Linfócito T / SARS-CoV-2 / COVID-19 Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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