Exosomes derived from PC-3 cells suppress osteoclast differentiation by downregulating miR-148a and blocking the PI3K/AKT/mTOR pathway.

Tian, Gaoqiang; Hu, Konghe; Qiu, Sujun; Xie, Yingming; Cao, Yanlin; Ni, Songjia; Zhang, Lifang.

Afiliação

Tian G; Department of Spine Surgery, The Affiliated Yuebei People's Hospital of Shantou University Medical College, Shaoguan, Guangdong 512025, P.R. China.
Hu K; Department of Spine Surgery, The Affiliated Yuebei People's Hospital of Shantou University Medical College, Shaoguan, Guangdong 512025, P.R. China.
Qiu S; Department of Orthopedics, Zhujiang Hospital, The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510280, P.R. China.
Xie Y; Department of Orthopedics, Zhujiang Hospital, The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510280, P.R. China.
Cao Y; Department of Orthopedics, Zhujiang Hospital, The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510280, P.R. China.
Ni S; Department of Orthopedics, Zhujiang Hospital, The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong 510280, P.R. China.
Zhang L; Department of Oral and Maxillofacial Surgery, Stomatological Hospital of Southern Medical University, Guangzhou, Guangdong 510250, P.R. China.

Exp Ther Med ; 22(5): 1304, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34630659