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Risk Factors for Perioperative Hemodynamic Instability in Pheochromocytoma: A Systematic Review and Meta-Analysis.
Urabe, Fumihiko; Kimura, Shoji; Iwatani, Kosuke; Takahashi, Kazuhiro; Ito, Kagenori; Tashiro, Kojiro; Tsuzuki, Shunsuke; Miki, Jun; Kimura, Takahiro; Furuta, Nozomu; Egawa, Shin.
Afiliação
  • Urabe F; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Kimura S; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Iwatani K; Department of Urology, The Jikei University Kashiwa Hospital, Chiba 277-8567, Japan.
  • Takahashi K; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Ito K; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Tashiro K; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Tsuzuki S; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Miki J; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Kimura T; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Furuta N; Department of Urology, The Jikei University Kashiwa Hospital, Chiba 277-8567, Japan.
  • Egawa S; Department of Urology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
J Clin Med ; 10(19)2021 Sep 30.
Article em En | MEDLINE | ID: mdl-34640549
ABSTRACT

OBJECTIVE:

To evaluate the risk factors of perioperative hemodynamic instability in pheochromocytoma, we conducted a systematic search of the literature using the Preferred Reporting Items for Systematic Reviews and Meta-analysis.

METHODS:

In April 2021, we systematically searched PubMed, the Cochrane library, and Scopus for relevant studies on the risk factors of perioperative hemodynamic instability of adrenalectomy in patients with pheochromocytoma, and we subjected the findings from those studies to formal meta-analysis.

RESULTS:

Our systematic review identified 14 studies involving 1725 patients, of which nine studies with 967 patients were eligible for meta-analysis. The results of meta-analysis showed that tumor size (odds ratio (OR) 1.14 for each increased cm, 95% confidence interval (CI) 1.03-1.26, z = 2.57) and urinary norepinephrine (OR, 1.51 95% CI 1.26-1.81; z = 4.50) were most closely associated with the occurrence of perioperative hemodynamic instability.

CONCLUSION:

These findings suggest that tumor size and urinary norepinephrine are important predictors and risk factors for perioperative hemodynamic instability in adrenalectomy for pheochromocytoma. Such findings may be of value to surgeons and anesthesiologists when considering or preparing for this procedure.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article