Bacteroides vulgatus and Bacteroides dorei predict immune-related adverse events in immune checkpoint blockade treatment of metastatic melanoma.

Usyk, Mykhaylo; Pandey, Abhishek; Hayes, Richard B; Moran, Una; Pavlick, Anna; Osman, Iman; Weber, Jeffrey S; Ahn, Jiyoung

Usyk, Mykhaylo; Pandey, Abhishek; Hayes, Richard B; Moran, Una; Pavlick, Anna; Osman, Iman; Weber, Jeffrey S; Ahn, Jiyoung.

Afiliação

Usyk M; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
Pandey A; NYU Laura and Isaac Perlmutter Cancer Center, New York, NY, USA.
Hayes RB; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA.
Moran U; NYU Laura and Isaac Perlmutter Cancer Center, New York, NY, USA.
Pavlick A; NYU Laura and Isaac Perlmutter Cancer Center, New York, NY, USA.
Osman I; The Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, NY, USA.
Weber JS; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA.
Ahn J; NYU Laura and Isaac Perlmutter Cancer Center, New York, NY, USA.

Genome Med ; 13(1): 160, 2021 10 13.

Article em En | MEDLINE | ID: mdl-34641962

Assuntos

Bacteroides/fisiologia; Microbioma Gastrointestinal/fisiologia; Inibidores de Checkpoint Imunológico; Melanoma/imunologia; Melanoma/terapia; Algoritmos; Bacteroides/genética; Biomarcadores Tumorais; Fezes/microbiologia; Microbioma Gastrointestinal/genética; Humanos; Metagenoma; Metagenômica; Estudos Prospectivos; RNA Ribossômico 16S

Palavras-chave

Biomarkers; Immune-related adverse events; Melanoma; Microbiome; Prospective design; Survival; Toxicity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bacteroides / Microbioma Gastrointestinal / Inibidores de Checkpoint Imunológico / Melanoma Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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