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Video-assisted mediastinoscopic and laparoscopic transhiatal esophagectomy for esophageal cancer.
Shi, Kefeng; Qian, Rulin; Zhang, Xiao; Jin, Zhe; Lin, Tao; Lang, Baoping; Wang, Guolei; Cui, Dong; Zhang, Binbin; Hua, Xionghuai.
Afiliação
  • Shi K; Department of Thoracic Surgery, Henan Provincial Chest Hospital, No. 1 Weiwu Road, Zhengzhou, 450000, China.
  • Qian R; Department of Thoracic Surgery, Henan Provincial Chest Hospital, No. 1 Weiwu Road, Zhengzhou, 450000, China. 13633860396@163.com.
  • Zhang X; Department of Thoracic Surgery, Luoyang Central Hospital Affiliated To Zhengzhou University, No. 288 Zhongzhou Middle Road, Luoyang, 471099, China. txzxd@163.com.
  • Jin Z; Department of Thoracic Surgery, Nanyang Central Hospital, Nanyang, 473003, China.
  • Lin T; Department of Thoracic Surgery, Nanyang Central Hospital, Nanyang, 473003, China.
  • Lang B; Department of Thoracic Surgery, Luoyang Central Hospital Affiliated To Zhengzhou University, No. 288 Zhongzhou Middle Road, Luoyang, 471099, China.
  • Wang G; Department of Thoracic Surgery, Henan Provincial Chest Hospital, No. 1 Weiwu Road, Zhengzhou, 450000, China.
  • Cui D; Department of Thoracic Surgery, Henan Provincial Chest Hospital, No. 1 Weiwu Road, Zhengzhou, 450000, China.
  • Zhang B; Department of Thoracic Surgery, Henan Provincial Chest Hospital, No. 1 Weiwu Road, Zhengzhou, 450000, China.
  • Hua X; Department of Thoracic Surgery, Henan Provincial Chest Hospital, No. 1 Weiwu Road, Zhengzhou, 450000, China.
Surg Endosc ; 36(6): 4207-4214, 2022 06.
Article em En | MEDLINE | ID: mdl-34642798
ABSTRACT

BACKGROUND:

Mediastinoscopy was originally applied for lymph node biopsy and mediastinal tumor resection. Improved video imaging with spreadable working channels enabled mediastinoscopy for inspection and tissue biopsy in the superior mediastinum but it is rarely used in minimally invasive esophageal cancer surgery. In this prospective trial, the practicability and security of spreadable video-assisted mediastinoscopic combined with laparoscopic transhiatal esophagectomy (VAME) with video-assisted thoracoscopic esophagectomy (VATE) were compared.

METHODS:

A total of 200 eligible patients with esophageal squamous cell carcinoma were randomly divided into VAME or VATE groups. Early postoperative outcomes and lymph node dissection between the two groups were compared.

RESULTS:

The operation time was significantly shorter (164.3 ± 47.0 min vs. 265.4 ± 47.2 min, P < 0.001), the number of dissected lymph nodes was less (15.8 ± 4.5 vs. 20.3 ± 6.5, P < 0.001), and the intraoperative blood loss was also significantly reduced (94.7 ± 56.7 mL vs. 184.4 ± 65.2 mL, P < 0.001) in the VAME compared to the VATE group, respectively. The incidence of pneumonia was lower (7% vs. 29%; P < 0.001) and the length of hospital stay was shorter in the VAME group compared to the VATE group (18.0 ± 7.6 days vs. 23.2 ± 7.2, P < 0.001, respectively). The chyle leak incidence appeared to be lower in the VAME group but statistical significance was not reached (1% vs. 4%; P = 0.369). There were no differences in the incidence of anastomotic leakages and recurrent laryngeal nerve paralysis between the groups. No 30-day mortality occurred in any of the cases.

CONCLUSION:

VAME appears to be a practicable and secure method for esophagectomy but needs further proof of concept. CLINICAL REGISTRATION NUMBER Registered at Chinese Clinical Trial Registry, ChiCTR1900022797.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Laparoscopia / Carcinoma de Células Escamosas do Esôfago Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Laparoscopia / Carcinoma de Células Escamosas do Esôfago Idioma: En Ano de publicação: 2022 Tipo de documento: Article