Reductive Ni-catalysis for stereoselective carboarylation of terminal aryl alkynes.

ABSTRACT

Stereoselective dicarbofunctionalization of terminal aryl alkynes has been achieved through reductive Ni-catalysis. The exclusive regioselective and anti-addition selective alkylarylation of terminal alkynes is accomplished using alkyl iodide and aryl iodide as electrophilic coupling partners in the presence of NiBr2 as the catalyst and Mn as an inexpensive reductant.