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Somatic cell and innate immune responses in mammary glands of lactating cows to intramammary infusion of Bifidobacterium breve at pre-drying off period.
Nagahata, Hajime; Kine, Mari; Watanabe, Hisato; Tanaka, Ai; Takahashi, Aoi; Gondaira, Satoshi; Higuchi, Hidetoshi.
Afiliação
  • Nagahata H; Department of Veterinary Associated Science, Faculty of Veterinary Medicine, Okayama University of Science, Ikoinooka 1-3, Imabari, Ehime 794-8555, Japan.
  • Kine M; Animal Health Unit, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Bunkyodai-Midori 582, Ebetsu, Hokkaido 069-8501, Japan.
  • Watanabe H; Animal Health Unit, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Bunkyodai-Midori 582, Ebetsu, Hokkaido 069-8501, Japan.
  • Tanaka A; Animal Health Unit, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Bunkyodai-Midori 582, Ebetsu, Hokkaido 069-8501, Japan.
  • Takahashi A; Animal Health Unit, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Bunkyodai-Midori 582, Ebetsu, Hokkaido 069-8501, Japan.
  • Gondaira S; Animal Health Unit, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Bunkyodai-Midori 582, Ebetsu, Hokkaido 069-8501, Japan.
  • Higuchi H; Animal Health Unit, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Bunkyodai-Midori 582, Ebetsu, Hokkaido 069-8501, Japan.
J Vet Med Sci ; 83(12): 1845-1851, 2021 Dec 02.
Article em En | MEDLINE | ID: mdl-34645724
ABSTRACT
Intramammary infusion of Bifidobacterium breve (B. breve)-induced somatic cell (SC) counts, chemiluminescent response (CL), lactoferrin (LF) concentrations and mastitis-causing pathogens from quarters with subclinical mastitis were measured to evaluate innate immune response of mammary glands in dairy cows at 3 to 4 weeks before drying off. SC counts in 7 quarters of 7 control cows and 5 quarters of 6 cows with mastitis increased markedly on day 1 and SC values in control cows were significantly (P<0.05) increased and returned to pre-infusion levels on day 5 after B. breve-infusion. CL values in both groups increased markedly on day 1 and then decreased after B. breve-infusion; however, CL values in cows with mastitis did not return to normal levels on day 5 and at postpartum. The CL values were highly correlated with their SC counts in milk from both groups. LF concentrations increased toward day 3 after B. breve-infusion and were higher in cows with mastitis. B. breve-infusion eliminated 16.6% (1/6) of pathogens from 6 quarters with chronic subclinical mastitis. B. breve-induced SC responses in quarters from 3 cows with mastitis showed characteristic patterns of recovery, persistent and new infections. B. breve-induced SC counts in quarters from the cows in the pre-drying off were lower (25.7-70.6%) than those of the cows in mid-lactation. The intrinsic innate immune response in cows on pre-drying off may be decreased and appears to be insufficient to eliminate pathogens from mammary gland in the pre-drying off.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças dos Bovinos / Bifidobacterium breve / Mastite Bovina Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças dos Bovinos / Bifidobacterium breve / Mastite Bovina Idioma: En Ano de publicação: 2021 Tipo de documento: Article