DNA Double-Strand Breaks Induced in Human Cells by Twelve Metallic Species: Quantitative Inter-Comparisons and Influence of the ATM Protein.

Viau, Muriel; Sonzogni, Laurène; Ferlazzo, Mélanie L; Berthel, Elise; Pereira, Sandrine; Bodgi, Larry; Granzotto, Adeline; Devic, Clément; Fervers, Béatrice; Charlet, Laurent; Foray, Nicolas

Viau, Muriel; Sonzogni, Laurène; Ferlazzo, Mélanie L; Berthel, Elise; Pereira, Sandrine; Bodgi, Larry; Granzotto, Adeline; Devic, Clément; Fervers, Béatrice; Charlet, Laurent; Foray, Nicolas.

Afiliação

Viau M; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.
Sonzogni L; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.
Ferlazzo ML; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.
Berthel E; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.
Pereira S; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.
Bodgi L; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.
Granzotto A; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.
Devic C; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.
Fervers B; Cancer & Environment Department, Centre Léon-Bérard, 69008 Lyon, France.
Charlet L; ISTerre Team, University Grenoble Alpes, 38000 Grenoble, France.
Foray N; Inserm, U1296 Unit, Radiation: Defense, Health, Environment, Centre Léon-Bérard, 69008 Lyon, France.

Biomolecules ; 11(10)2021 10 05.

Article em En | MEDLINE | ID: mdl-34680095

Assuntos

Proteínas Mutadas de Ataxia Telangiectasia/química; Quebras de DNA de Cadeia Dupla/efeitos dos fármacos; Reparo do DNA/efeitos dos fármacos; Metais/química; Alumínio/farmacologia; Proteínas Mutadas de Ataxia Telangiectasia/efeitos dos fármacos; Proteínas Mutadas de Ataxia Telangiectasia/efeitos da radiação; Cádmio/farmacologia; Cromo/farmacologia; Cobre/farmacologia; Reparo do DNA/efeitos da radiação; Humanos; Ferro/farmacologia; Chumbo/farmacologia; Metais/farmacologia; Metais/toxicidade; Níquel/farmacologia; Paládio/farmacologia; Zinco/farmacologia

Palavras-chave

ATM; DNA double-strand breaks; metal carcinogenesis; metal toxicity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reparo do DNA / Quebras de DNA de Cadeia Dupla / Proteínas Mutadas de Ataxia Telangiectasia / Metais Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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