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An Afucosylated Anti-CD32b Monoclonal Antibody Induced Platelet-Mediated Adverse Events in a Human Fcγ Receptor Transgenic Mouse Model and Its Potential Human Translatability.
Wolf, Babette; Jeliazkova-Mecheva, Valentina; Del Rio-Espinola, Alberto; Boisclair, Julie; Walker, Dana; Cochin De Billy, Benjamin; Flaherty, Meghan; Flandre, Thierry.
Afiliação
  • Wolf B; Novartis Institutes for BioMedical Research, Preclinical Safety, 4002 Basel, Switzerland.
  • Jeliazkova-Mecheva V; Novartis Institutes for BioMedical Research, Preclinical Safety, Cambridge, Massachusetts 02139, USA.
  • Del Rio-Espinola A; Novartis Institutes for BioMedical Research, Preclinical Safety, 4002 Basel, Switzerland.
  • Boisclair J; Novartis Institutes for BioMedical Research, Preclinical Safety, 4002 Basel, Switzerland.
  • Walker D; Novartis Institutes for BioMedical Research, Preclinical Safety, Cambridge, Massachusetts 02139, USA.
  • Cochin De Billy B; Novartis Institutes for BioMedical Research, Preclinical Safety, 4002 Basel, Switzerland.
  • Flaherty M; Novartis Institutes for BioMedical Research, Preclinical Safety, Cambridge, Massachusetts 02139, USA.
  • Flandre T; Novartis Institutes for BioMedical Research, Preclinical Safety, 4002 Basel, Switzerland.
Toxicol Sci ; 185(1): 89-104, 2021 12 28.
Article em En | MEDLINE | ID: mdl-34687301
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Receptores de IgG Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Receptores de IgG Idioma: En Ano de publicação: 2021 Tipo de documento: Article