The MttB superfamily member MtyB from the human gut symbiont Eubacterium limosum is a cobalamin-dependent Î³-butyrobetaine methyltransferase.

Ellenbogen, Jared B; Jiang, Ruisheng; Kountz, Duncan J; Zhang, Liwen; Krzycki, Joseph A

Ellenbogen, Jared B; Jiang, Ruisheng; Kountz, Duncan J; Zhang, Liwen; Krzycki, Joseph A.

Afiliação

Ellenbogen JB; Department of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Jiang R; Department of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Kountz DJ; Department of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Zhang L; Campus Chemical Instrument Center Mass Spectrometry and Proteomics Facility, The Ohio State University, Columbus, Ohio, USA.
Krzycki JA; Department of Microbiology, The Ohio State University, Columbus, Ohio, USA; The Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio, USA. Electronic address: Krzycki.1@osu.edu.

J Biol Chem ; 297(5): 101327, 2021 11.

Article em En | MEDLINE | ID: mdl-34688665

Assuntos

Proteínas de Bactérias/química; Betaína/análogos & derivados; Carnitina/química; Eubacterium/enzimologia; Metiltransferases/química; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Betaína/química; Betaína/metabolismo; Carnitina/genética; Carnitina/metabolismo; Eubacterium/genética; Microbioma Gastrointestinal; Humanos; Metiltransferases/genética; Metiltransferases/metabolismo; Simbiose

Palavras-chave

L-carnitine; acetogenesis; bacterial metabolism; cobalamin; energy metabolism; enzyme catalysis; folate; microbiology; microbiome; one carbon metabolism; Î³-butyrobetaine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Betaína / Carnitina / Eubacterium / Metiltransferases Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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