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Real-Time Genomic Surveillance during the 2021 Re-Emergence of the Yellow Fever Virus in Rio Grande do Sul State, Brazil.
Andrade, Miguel de S; Campos, Fabrício S; Campos, Aline A S; Abreu, Filipe V S; Melo, Fernando L; Sevá, Anaiá da P; Cardoso, Jader da C; Dos Santos, Edmilson; Born, Lucas C; Silva, Cláudia M D da; Müller, Nicolas F D; Oliveira, Cirilo H de; Silva, Alex J J da; Simonini-Teixeira, Danilo; Bernal-Valle, Sofía; Mares-Guia, Maria A M M; Albuquerque, George R; Romano, Alessandro P M; Franco, Ana C; Ribeiro, Bergmann M; Roehe, Paulo M; Almeida, Marco A B de.
Afiliação
  • Andrade MS; Baculovirus Laboratory, Department of Cell Biology, Institute of Biological Sciences, University of Brasilia, Brasília 70910-900, Distrito Federal, Brazil.
  • Campos FS; Bioinformatics and Biotechnology Laboratory, Campus of Gurupi, Federal University of Tocantins, Gurupi 77410-570, Tocantins, Brazil.
  • Campos AAS; State Center of Health Surveillance, Rio Grande do Sul State Health Department, Porto Alegre 90610-000, Rio Grande do Sul, Brazil.
  • Abreu FVS; Insect Behavior Laboratory, Federal Institute of Northern Minas Gerais, Salinas 39560-000, Minas Gerais, Brazil.
  • Melo FL; Baculovirus Laboratory, Department of Cell Biology, Institute of Biological Sciences, University of Brasilia, Brasília 70910-900, Distrito Federal, Brazil.
  • Sevá ADP; Department of Agricultural and Environmental Sciences, Santa Cruz State University, Ilhéus 45662-900, Bahia, Brazil.
  • Cardoso JDC; State Center of Health Surveillance, Rio Grande do Sul State Health Department, Porto Alegre 90610-000, Rio Grande do Sul, Brazil.
  • Dos Santos E; State Center of Health Surveillance, Rio Grande do Sul State Health Department, Porto Alegre 90610-000, Rio Grande do Sul, Brazil.
  • Born LC; State Center of Health Surveillance, Rio Grande do Sul State Health Department, Porto Alegre 90610-000, Rio Grande do Sul, Brazil.
  • Silva CMDD; State Center of Health Surveillance, Rio Grande do Sul State Health Department, Porto Alegre 90610-000, Rio Grande do Sul, Brazil.
  • Müller NFD; Institute of Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre 90050-170, Rio Grande do Sul, Brazil.
  • Oliveira CH; Insect Behavior Laboratory, Federal Institute of Northern Minas Gerais, Salinas 39560-000, Minas Gerais, Brazil.
  • Silva AJJD; Insect Behavior Laboratory, Federal Institute of Northern Minas Gerais, Salinas 39560-000, Minas Gerais, Brazil.
  • Simonini-Teixeira D; Department of Agricultural and Environmental Sciences, Santa Cruz State University, Ilhéus 45662-900, Bahia, Brazil.
  • Bernal-Valle S; Department of Agricultural and Environmental Sciences, Santa Cruz State University, Ilhéus 45662-900, Bahia, Brazil.
  • Mares-Guia MAMM; Flavivirus Laboratory, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-360, Rio de Janeiro, Brazil.
  • Albuquerque GR; Department of Agricultural and Environmental Sciences, Santa Cruz State University, Ilhéus 45662-900, Bahia, Brazil.
  • Romano APM; General Coordination of Arbovirus Surveillance, Ministry of Health, Brasília 70058-900, Distrito Federal, Brazil.
  • Franco AC; Institute of Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre 90050-170, Rio Grande do Sul, Brazil.
  • Ribeiro BM; Baculovirus Laboratory, Department of Cell Biology, Institute of Biological Sciences, University of Brasilia, Brasília 70910-900, Distrito Federal, Brazil.
  • Roehe PM; Institute of Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre 90050-170, Rio Grande do Sul, Brazil.
  • Almeida MAB; State Center of Health Surveillance, Rio Grande do Sul State Health Department, Porto Alegre 90610-000, Rio Grande do Sul, Brazil.
Viruses ; 13(10)2021 10 01.
Article em En | MEDLINE | ID: mdl-34696408
ABSTRACT
The 2021 re-emergence of yellow fever in non-human primates in the state of Rio Grande do Sul (RS), southernmost Brazil, resulted in the death of many howler monkeys (genus Alouatta) and led the state to declare a Public Health Emergency of State Importance, despite no human cases reported. In this study, near-complete genomes of yellow fever virus (YFV) recovered from the outbreak were sequenced and examined aiming at a better understanding of the phylogenetic relationships and the spatio-temporal dynamics of the virus distribution. Our results suggest that the most likely sequence of events involved the reintroduction of YFV from the state of São Paulo to RS through the states of Paraná and Santa Catarina, by the end of 2020. These findings reinforce the role of genomic surveillance in determining the pathways of distribution of the virus and in providing references for the implementation of preventive measures for populations in high risk areas.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Febre Amarela / Vírus da Febre Amarela Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Febre Amarela / Vírus da Febre Amarela Idioma: En Ano de publicação: 2021 Tipo de documento: Article