Prospects for liver fluke vaccines.
Exp Parasitol
; 230: 108170, 2021 Nov.
Article
em En
| MEDLINE
| ID: mdl-34699916
ABSTRACT
Fasciola spp., Opisthorchis spp. and Clonorchis sinensis are common liver flukes that can cause a variety of diseases, mainly cholangiocarcinoma induced by clonorchiasis and liver damage and associated pathology induced by fascioliasis. Because these trematodes are parasites of humans and domestic animals, they have greatly affected the economy of agricultural industries and public health worldwide. Due to the emergence of drug resistance and the living habits of flukes, among other reasons, a possibility of reinfection remains even when antiparasitic drugs are used. Therefore, developing a safe, efficient and cost-effective vaccine against trematodes is an important goal. Here, we briefly describe the progress in the development of vaccines against liver flukes. Related innovations may provide effective protection against these helminths and the diseases that they cause.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Opisthorchis
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Vacinas
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Clonorchis sinensis
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Fasciola hepatica
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Hepatopatias Parasitárias
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article