The FMR1 Premutation Phenotype and Mother-Youth Synchrony in Fragile X Syndrome.
Am J Intellect Dev Disabil
; 126(6): 443-459, 2021 11 01.
Article
em En
| MEDLINE
| ID: mdl-34700350
ABSTRACT
A subset of mothers who carry the FMR1 premutation may express a unique phenotype. The relationship between the FMR1 phenotype and mother-child interaction in families with fragile X-associated disorders has not been well characterized, despite the importance of high-quality mother-child interaction for child development. This study examined the association between the FMR1 phenotype and the quality of interactions between mothers and their adolescent/young adult sons with fragile X syndrome. Mother-youth synchrony was coded from a dyadic interaction. Maternal anxiety and depression symptoms, executive function deficits, and pragmatic language difficulties were evaluated. Results indicated that pragmatic language was associated with mother-youth synchrony. These findings highlight the importance of family-centered intervention practices for families with fragile X-associated disorders.
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1
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Cromossomo X Frágil
/
Mães
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article