Natural language word embeddings as a glimpse into healthcare language and associated mortality surrounding end of life.

ABSTRACT

OBJECTIVES: To clarify real-world linguistic nuances around dying in hospital as well as inaccuracy in individual-level prognostication to support advance care planning and personalised discussions on limitation of life sustaining treatment (LST). DESIGN: Retrospective cross-sectional study of real-world clinical data. SETTING: Secondary care, urban and suburban teaching hospitals. PARTICIPANTS: All inpatients in 12-month period from 1 October 2018 to 30 September 2019. METHODS: Using unsupervised natural language processing, word embedding in latent space was used to generate phrase clusters with most similar semantic embeddings to 'Ceiling of Treatment' and their prognostication value. RESULTS: Word embeddings with most similarity to 'Ceiling of Treatment' clustered around phrases describing end-of-life care, ceiling of care and LST discussions. The phrases have differing prognostic profile with the highest 7-day mortality in the phrases most explicitly referring to end of life-'Withdrawal of care' (56.7%), 'terminal care/end of life care' (57.5%) and 'un-survivable' (57.6%). CONCLUSION: Vocabulary used at end-of-life discussions are diverse and has a range of associations to 7-day mortality. This highlights the importance of correct application of terminology during LST and end-of-life discussions.