Nanomedicine for increasing the oral bioavailability of cancer treatments.
J Nanobiotechnology
; 19(1): 354, 2021 Oct 30.
Article
em En
| MEDLINE
| ID: mdl-34717658
ABSTRACT
Oral administration is an appealing route of delivering cancer treatments. However, the gastrointestinal tract is characterized by specific and efficient physical, chemical, and biological barriers that decrease the bioavailability of medications, including chemotherapeutics. In recent decades, the fields of material science and nanomedicine have generated several delivery platforms with high potential for overcoming multiple barriers associated to oral administration. This review describes the properties of several nanodelivery systems that improve the bioavailability of orally administered therapeutics, highlighting their advantages and disadvantages in generating successful anticancer oral nanomedicines.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Nanomedicina
/
Neoplasias
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Antineoplásicos
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article