Low-concentration povidone-iodine for the prevention of intraocular infections in ophthalmic surgery.
Curr Opin Ophthalmol
; 33(1): 28-34, 2022 Jan 01.
Article
em En
| MEDLINE
| ID: mdl-34720096
ABSTRACT
PURPOSE OF REVIEW Endophthamitis following intraocular surgery is rare using current antiseptic techniques, such as single application of 5% povidone-iodine to the ocular surface and adjuvant topical or intracameral antibiotics. Challenges remain, however, including increased multidrug-resistant bacterial endophthalmitis, increased fungal endophthalmitis, and the low but nonzero endophthalmitis rate attributable to the typical bacteria that colonize the ocular surface. RECENT FINDINGS:
Povidone-iodine has a wide spectrum of activity, including activity against novel pathogens, such as SARS-CoV-2. Povidone-iodine alternatives, such as hypochlorous acid can have significantly less efficacy in vitro against endophthalmitis isolates. Repetitive application of dilute povidone-iodine has an excellent safety profile and strong evidence base for efficacy.SUMMARY:
Povidone-iodine is widely available, inexpensive, and commonly used by ophthalmologists. The repetitive application of dilute povidone-iodine is a well studied, well tolerated, and efficacious way to transiently sterilize the ocular surface during intraocular surgery. Additional benefits include activity against multidrug-resistant bacteria, fungi, and lack of inducible resistance.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Endoftalmite
/
COVID-19
/
Anti-Infecciosos Locais
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article