Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis.

Zhang, Dandan; Zhao, Shengnan; Zhang, Zhijie; Xu, Danfeng; Lian, Di; Wu, Jing; He, Dake; Sun, Kun; Li, Ling

Zhang, Dandan; Zhao, Shengnan; Zhang, Zhijie; Xu, Danfeng; Lian, Di; Wu, Jing; He, Dake; Sun, Kun; Li, Ling.

Afiliação

Zhang D; Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China.
Zhao S; Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China.
Zhang Z; Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China.
Xu D; Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China.
Lian D; Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China.
Wu J; Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China.
He D; Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China.
Sun K; Department of Pediatric Cardiology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China. sunkun@xinhuamed.com.cn.
Li L; Department of Pediatric Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Kongjiang Road 1665, Shanghai, 200092, China. liling@xinhuamed.com.cn.

J Neuroinflammation ; 18(1): 253, 2021 Nov 02.

Article em En | MEDLINE | ID: mdl-34727939

Assuntos

Hipocampo/patologia; Meningite Pneumocócica/metabolismo; Proteínas do Tecido Nervoso/metabolismo; Neurogênese/fisiologia; Doenças Neuroinflamatórias/patologia; Receptores de Fatores de Crescimento/metabolismo; Animais; Modelos Animais de Doenças; Hipocampo/efeitos dos fármacos; Hipocampo/metabolismo; Isoleucina/análogos & derivados; Isoleucina/farmacologia; Morfolinas/farmacologia; Neurogênese/efeitos dos fármacos; Doenças Neuroinflamatórias/metabolismo; Ratos; Ratos Sprague-Dawley

Palavras-chave

Brain injury; Hippocampal neurogenesis; Neuroinflammation; Streptococcus pneumoniae meningitis; p75 neurotrophin receptor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Fatores de Crescimento / Neurogênese / Doenças Neuroinflamatórias / Hipocampo / Meningite Pneumocócica / Proteínas do Tecido Nervoso Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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