Computed Tomography and Clinical Analysis of Ovarian Mucinous Tumors in Adolescent Patients.

ABSTRACT

STUDY OBJECTIVE: To investigate the clinical and computed tomography features of ovarian mucinous tumors in children and adolescents. DESIGN, SETTING, AND PARTICIPANTS: A retrospective analysis of clinical and preoperative computed tomography (CT) data was performed in 59 patients who were 20 years or younger with ovarian mucinous tumors confirmed by histopathology. Patients' age, medical history, symptoms, tumor marker levels, and CT imaging findings were recorded. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Identification of the clinical and CT features of ovarian mucinous tumors in pediatric and adolescent patients. RESULTS: There were 41 mucinous cystadenomas in 39 cases, 12 borderline mucinous cystadenomas in 11 cases, and 9 mucinous cystadenocarcinomas in 9 patients. A total of 55 tumors were multilocular (55/62, 88.7%), including fewer than 10 loculations in 23 tumors, 10-20 loculations in 17 tumors, and over 20 loculations in 15 tumors. Eleven borderline mucinous cystadenomas were multilocular (11/12, 91.7%), with over 10 loculations in 7 tumors (7/12, 58.3%). Twelve tumors appeared as multilocular cystic-solid (12/62, 19.4%), and a case of mucinous cystadenocarcinoma was predominantly solid (1/62, 1.6%). Seventeen tumors showed honeycomb sign and stained glass appearance. Six mural nodules, with sizes ranging from 1.1 to 3.5 cm (average 2.8 cm), were found in borderline mucinous cystadenoma and mucinous cystadenocarcinoma. CONCLUSIONS: The CT findings of ovarian mucinous tumors in children are characteristic. The preoperative CT is helpful in making differential diagnoses.