Decoding the chemical composition and pharmacological mechanisms of Jiedu Tongluo Tiaogan Formula using high-performance liquid chromatography coupled with network pharmacology-based investigation.

Zhang, Qi; Piao, Chunli; Jin, Wenqi; Jin, De; Wang, Han; Tang, Cheng; Zhao, Xiaohua; Zhang, Naiwen; Gao, Shengnan; Lian, Fengmei

Zhang, Qi; Piao, Chunli; Jin, Wenqi; Jin, De; Wang, Han; Tang, Cheng; Zhao, Xiaohua; Zhang, Naiwen; Gao, Shengnan; Lian, Fengmei.

Afiliação

Zhang Q; Changchun University of Chinese Medicine, Changchun 130021, Jilin Province, P.R. China.
Piao C; Shenzhen Hospital, Guangzhou University of Chinese Medicine (Futian), Shenzhen 518000, Guangdong Province, P.R. China.
Jin W; Changchun University of Chinese Medicine, Changchun 130021, Jilin Province, P.R. China.
Jin; Guang'anmen Hospital, China Academy of Chinese Medical Science, Beijing 100700, P.R. China.
Wang H; Guang'anmen Hospital, China Academy of Chinese Medical Science, Beijing 100700, P.R. China.
Tang C; Changchun University of Chinese Medicine, Changchun 130021, Jilin Province, P.R. China.
Zhao X; Shenzhen Hospital, Guangzhou University of Chinese Medicine (Futian), Shenzhen 518000, Guangdong Province, P.R. China.
Zhang N; Shenzhen Hospital, Guangzhou University of Chinese Medicine (Futian), Shenzhen 518000, Guangdong Province, P.R. China.
Gao S; Shenzhen Hospital, Guangzhou University of Chinese Medicine (Futian), Shenzhen 518000, Guangdong Province, P.R. China.
Lian F; Guang'anmen Hospital, China Academy of Chinese Medical Science, Beijing 100700, P.R. China.

Aging (Albany NY) ; 13(21): 24290-24312, 2021 11 05.

Article em En | MEDLINE | ID: mdl-34740995

Assuntos

Cromatografia Líquida de Alta Pressão/métodos; Medicamentos de Ervas Chinesas; Farmacologia em Rede/métodos; Diabetes Mellitus Tipo 2/metabolismo; Medicamentos de Ervas Chinesas/análise; Medicamentos de Ervas Chinesas/química; Medicamentos de Ervas Chinesas/farmacologia; Humanos; Simulação de Acoplamento Molecular; Mapas de Interação de Proteínas/efeitos dos fármacos

Palavras-chave

Jiedu Tongluo Tiaogan Formula; PI3K/Akt signaling pathway; network pharmacology; traditional Chinese medicine; type 2 diabetes mellitus

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medicamentos de Ervas Chinesas / Cromatografia Líquida de Alta Pressão / Farmacologia em Rede Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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