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A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice.
Mao, Tianyang; Israelow, Benjamin; Lucas, Carolina; Vogels, Chantal B F; Gomez-Calvo, Maria Luisa; Fedorova, Olga; Breban, Mallery I; Menasche, Bridget L; Dong, Huiping; Linehan, Melissa; Wilen, Craig B; Landry, Marie L; Grubaugh, Nathan D; Pyle, Anna M; Iwasaki, Akiko.
Afiliação
  • Mao T; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
  • Israelow B; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
  • Lucas C; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT.
  • Vogels CBF; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
  • Gomez-Calvo ML; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT.
  • Fedorova O; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
  • Breban MI; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT.
  • Menasche BL; Howard Hughes Medical Institute, Chevy Chase, MD.
  • Dong H; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT.
  • Linehan M; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT.
  • Wilen CB; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
  • Grubaugh ND; Department of Immunobiology, Yale School of Medicine, New Haven, CT.
  • Pyle AM; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT.
  • Iwasaki A; Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT.
J Exp Med ; 219(1)2022 01 03.
Article em En | MEDLINE | ID: mdl-34757384

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / RNA / SARS-CoV-2 / Tratamento Farmacológico da COVID-19 Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / RNA / SARS-CoV-2 / Tratamento Farmacológico da COVID-19 Idioma: En Ano de publicação: 2022 Tipo de documento: Article