Stromal Barrier-Dismantled Nanodrill-Like and Cancer Cell-Targeted pH-Responsive Polymeric Micelles for Further Enhancing the Anticancer Efficacy of Doxorubicin.

Zhou, Chuhang; Hu, Xinping; Liu, Qi; Wang, Leqi; Zhou, Yuanhang; Jin, Yao; Ma, Yining; Liu, Yan

Zhou, Chuhang; Hu, Xinping; Liu, Qi; Wang, Leqi; Zhou, Yuanhang; Jin, Yao; Ma, Yining; Liu, Yan.

Afiliação

Zhou C; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Hu X; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Liu Q; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Wang L; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Zhou Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Jin Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Ma Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Liu Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.

ACS Biomater Sci Eng ; 7(12): 5690-5705, 2021 12 13.

Article em En | MEDLINE | ID: mdl-34761919

Assuntos

Micelas; Neoplasias; Animais; Doxorrubicina/farmacologia; Concentração de Íons de Hidrogênio; Camundongos; Camundongos Nus; Neoplasias/tratamento farmacológico; Distribuição Tecidual

Palavras-chave

cancer-associated fibroblasts; fibroblast activation protein α; folate targeting; pH-responsive polymeric micelles; tumor stromal barrier

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Micelas / Neoplasias Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Micelas / Neoplasias Idioma: En Ano de publicação: 2021 Tipo de documento: Article