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Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma.
Tumino, Nicola; Weber, Gerrit; Besi, Francesca; Del Bufalo, Francesca; Bertaina, Valentina; Paci, Paola; Quatrini, Linda; Antonucci, Laura; Sinibaldi, Matilde; Quintarelli, Concetta; Maggi, Enrico; De Angelis, Biagio; Locatelli, Franco; Moretta, Lorenzo; Vacca, Paola; Caruana, Ignazio.
Afiliação
  • Tumino N; Immunology Research Area, IRCCS Bambino Gesù Children's Hospital, Viale San Paolo 15, 00146, Rome, Italy.
  • Weber G; Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.
  • Besi F; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation University Children's Hospital of Würzburg, 97080, Würzburg, Germany.
  • Del Bufalo F; Immunology Research Area, IRCCS Bambino Gesù Children's Hospital, Viale San Paolo 15, 00146, Rome, Italy.
  • Bertaina V; Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.
  • Paci P; Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.
  • Quatrini L; Institute for Systems Analysis and Computer Science "Antonio Ruberti", National Research Council, Rome, Italy.
  • Antonucci L; Immunology Research Area, IRCCS Bambino Gesù Children's Hospital, Viale San Paolo 15, 00146, Rome, Italy.
  • Sinibaldi M; Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.
  • Quintarelli C; Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.
  • Maggi E; Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.
  • De Angelis B; Immunology Research Area, IRCCS Bambino Gesù Children's Hospital, Viale San Paolo 15, 00146, Rome, Italy.
  • Locatelli F; Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy.
  • Moretta L; Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Piazza Sant'Onofrio, 4, 00165, Rome, Italy. franco.locatelli@opbg.net.
  • Vacca P; Department of Maternal, Infantile, and Urological Sciences, Sapienza University of Rome, Rome, Italy. franco.locatelli@opbg.net.
  • Caruana I; Immunology Research Area, IRCCS Bambino Gesù Children's Hospital, Viale San Paolo 15, 00146, Rome, Italy. lorenzo.moretta@opbg.net.
J Hematol Oncol ; 14(1): 191, 2021 11 12.
Article em En | MEDLINE | ID: mdl-34772439
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoterapia Adotiva / Células Supressoras Mieloides / Neuroblastoma Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoterapia Adotiva / Células Supressoras Mieloides / Neuroblastoma Idioma: En Ano de publicação: 2021 Tipo de documento: Article