Epigenetic quantification of circulating immune cells in peripheral blood of triple-negative breast cancer patients.

Manoochehri, Mehdi; Hielscher, Thomas; Borhani, Nasim; Gerhäuser, Clarissa; Fletcher, Olivia; Swerdlow, Anthony J; Ko, Yon-Dschun; Brauch, Hiltrud; Brüning, Thomas; Hamann, Ute

Manoochehri, Mehdi; Hielscher, Thomas; Borhani, Nasim; Gerhäuser, Clarissa; Fletcher, Olivia; Swerdlow, Anthony J; Ko, Yon-Dschun; Brauch, Hiltrud; Brüning, Thomas; Hamann, Ute.

Afiliação

Manoochehri M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany. mehdi.manoochehri@igb.fraunhofer.de.
Hielscher T; Department of in-Vitro Diagnostics, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany. mehdi.manoochehri@igb.fraunhofer.de.
Borhani N; Division of Biostatistics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Gerhäuser C; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany.
Fletcher O; Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Swerdlow AJ; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Ko YD; The Institute of Cancer Research, London, UK.
Brauch H; Division of Genetics and Epidemiology and Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.
Brüning T; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, 53113, Bonn, Germany.
Hamann U; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, 70376, Stuttgart, Germany.

Clin Epigenetics ; 13(1): 207, 2021 11 17.

Article em En | MEDLINE | ID: mdl-34789319

Assuntos

Contagem de Leucócitos/estatística & dados numéricos; Neoplasias de Mama Triplo Negativas/genética; Adulto; Estudos de Casos e Controles; Metilação de DNA/genética; Metilação de DNA/imunologia; Epigenômica/métodos; Epigenômica/estatística & dados numéricos; Feminino; Humanos; Contagem de Leucócitos/classificação; Contagem de Leucócitos/métodos; Modelos Logísticos; Pessoa de Meia-Idade; Razão de Chances; Modelos de Riscos Proporcionais; Neoplasias de Mama Triplo Negativas/sangue; Neoplasias de Mama Triplo Negativas/imunologia

Palavras-chave

DNA methylation in blood; Immune cell subtypes; TNBC risk; Triple-negative breast cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias de Mama Triplo Negativas / Contagem de Leucócitos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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