NIR light-controlled mitochondria-targeted delivery of carbon monoxide combined with histone deacetylase inhibition for synergistic anticancer therapy.

Tang, Qi; Yu, Ya-Ting; Zhang, Hai-Lin; Wang, Yi; Liu, Jing; Yang, Shi-Ping; Liu, Jin-Gang

Tang, Qi; Yu, Ya-Ting; Zhang, Hai-Lin; Wang, Yi; Liu, Jing; Yang, Shi-Ping; Liu, Jin-Gang.

Afiliação

Tang Q; Key Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237, PR China.
Yu YT; Key Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237, PR China.
Zhang HL; Key Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237, PR China.
Wang Y; Key Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237, PR China.
Liu J; Key Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237, PR China.
Yang SP; Key Lab of Resource Chemistry of MOE & Shanghai Key Lab of Rare Earth Functional Materials, Shanghai Normal University, Shanghai 200234, PR China.
Liu JG; Key Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237, PR China. Electronic address: liujingang@ecust.edu.cn.

J Inorg Biochem ; 226: 111656, 2022 01.

Article em En | MEDLINE | ID: mdl-34798307

Assuntos

Monóxido de Carbono; Sistemas de Liberação de Medicamentos; Inibidores de Histona Desacetilases; Raios Infravermelhos; Mitocôndrias/metabolismo; Neoplasias; Fototerapia; Apoptose/efeitos dos fármacos; Apoptose/efeitos da radiação; Monóxido de Carbono/farmacocinética; Monóxido de Carbono/farmacologia; Células HeLa; Inibidores de Histona Desacetilases/farmacocinética; Inibidores de Histona Desacetilases/farmacologia; Humanos; Neoplasias/tratamento farmacológico; Neoplasias/metabolismo

Palavras-chave

Carbon monoxide; Graphene quantum dots nanoplatform; Histone deacetylase inhibitor; Light-controlled release; Manganese carbonyl complexes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fototerapia / Monóxido de Carbono / Sistemas de Liberação de Medicamentos / Inibidores de Histona Desacetilases / Raios Infravermelhos / Mitocôndrias / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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