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Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIX.
Sheff, Joey G; Kelly, John F; Robotham, Anna; Sulea, Traian; Malenfant, Félix; L'Abbé, Denis; Duchesne, Mélanie; Pelletier, Alex; Lefebvre, Jean; Acel, Andrea; Parat, Marie; Gosselin, Mylene; Wu, Cunle; Fortin, Yves; Baardsnes, Jason; Van Faassen, Henk; Awrey, Shannon; Chafe, Shawn C; McDonald, Paul C; Dedhar, Shoukat; Lenferink, Anne E G.
Afiliação
  • Sheff JG; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, Canada.
  • Kelly JF; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, Canada.
  • Robotham A; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, Canada.
  • Sulea T; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Malenfant F; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • L'Abbé D; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Duchesne M; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Pelletier A; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Lefebvre J; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Acel A; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Parat M; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Gosselin M; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Wu C; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Fortin Y; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Baardsnes J; Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada.
  • Van Faassen H; Human Health Therapeutics Research Centre, National Research Council Canada, Ottawa, Ontario, Canada.
  • Awrey S; Department of Integrative Oncology, Bc Cancer Research Institute, Vancouver, BC, Canada.
  • Chafe SC; Department of Integrative Oncology, Bc Cancer Research Institute, Vancouver, BC, Canada.
  • McDonald PC; Department of Integrative Oncology, Bc Cancer Research Institute, Vancouver, BC, Canada.
  • Dedhar S; Department of Integrative Oncology, Bc Cancer Research Institute, Vancouver, BC, Canada.
  • Lenferink AEG; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada.
MAbs ; 13(1): 1997072, 2021.
Article em En | MEDLINE | ID: mdl-34812124
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medição da Troca de Deutério / Espectrometria de Massa com Troca Hidrogênio-Deutério Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medição da Troca de Deutério / Espectrometria de Massa com Troca Hidrogênio-Deutério Idioma: En Ano de publicação: 2021 Tipo de documento: Article